Availability and reliability assured with PYLARIFY

Consistent supply and distribution

Production 5 days a week
Multiple runs daily, and on weekends based on location
Coverage and reliability with robust radiopharmacy partners

PYLARIFY® is available nationwide¹

Over 1540 imaging centers
Available in 48 states and Puerto Rico

Expanded release times and longer half-life to meet high patient volume and enable more flexible patient scheduling

For information about ordering PYLARIFY  for your imaging site, and how to  get started, contact PYLARIFY Customer Support at 1-8‌00-9‌64-0446 M-F 8:30 am-8:00 pm ET, or email cspyl@lantheus.com.

PYLARIFY imaging site locator

Please enter your ZIP code to locate the nearest imaging site that offers PYLARIFY®.

Add Your Facility to Our Site Locator

For information about ordering PYLARIFY for your imaging site, and how to get started, contact
PYLARIFY Customer Support at 1-800-964-0446 1-8‌00-9‌64-0446 M-F 8:30 am-8:00 pm ET, or
email cspyl@lantheus.com.

This may not be a comprehensive list. The sites listed are provided as an informational resource only.

Progenics does not warrant, whether expressed or implied, that the Locator is accurate or complete. Progenics does not recommend or endorse any site included in the Locator for any purpose. It is your responsibility to select a site and you assume full responsibility for your interactions with any site you contact through the Locator.

Progenics is not responsible for the medical care or advice given by any site you choose to contact.

This free service provides a list of sites that may be qualified to provide PYLARIFY imaging. These sites do not pay a fee to be listed in the PYLARIFY Imaging Site Locator (“Locator”), and their participation does not impose any requirements on the manner in which they treat or provide services to patients. Participating sites are listed based on the geographical search information entered. Some of the participating sites may have other financial relationships with Progenics as recipients of research grants or other similar payments.

Sites may request to be removed from the Locator and Progenics retains the right to remove sites from the Locator.

To remove your facility from this list or request a specific change/update to a current site already in the Locator, contact us at pylcenters@lantheus.com.

Closest Imaging Sites That Offer
PYLARIFY® Near

Available Now

Alabama, Birmingham
Alabama, Mobile
Arizona, Phoenix
Arkansas, Little Rock
California, Culver City
California, Gilroy
California, Loma Linda
California, Los Angeles
California, Sacramento
California, San Francisco
Colorado, Denver
Florida, Fort Lauderdale
Florida, Jacksonville
Florida, Sanford
Florida, Tampa
Georgia, Atlanta
Georgia, Norcross
Illinois, Chicago
Illinois, Romeoville
Iowa, Davenport
Kansas, Kansas City
Kentucky, Louisville
Louisiana, Covington
Massachusetts, Boston
Massachusetts, Haverhill
Michigan, Detroit
Minnesota, Minneapolis
Missouri, Columbia
Missouri, Kansas City
Nevada, Las Vegas
New Jersey, Hackensack
New Jersey, Somerset
New Jersey, Totowa
New Mexico, Albuquerque
New York, Albany*
New York, Bronx
North Carolina, Raleigh
North Carolina, Winston-Salem
Ohio, Cincinnati
Ohio, Cleveland
Ohio, Oakwood Village
Oklahoma, Tulsa
Oregon, Portland
Pennsylvania, Philadelphia
Puerto Rico, San Juan
South Carolina, Columbia
Tennessee, Gray
Tennessee, Knoxville
Tennessee, Nashville
Texas, Austin
Texas, Dallas*
Texas, Houston*
Utah, Salt Lake City
Virginia, Sterling
Washington, Seattle
Washington, Spokane
West Virginia, Morgantown
Wisconsin, Milwaukee

Kentucky, Louisville
Louisiana, Covington
Massachusetts, Boston
Massachusetts, Haverhill
Michigan, Detroit
Minnesota, Minneapolis
Missouri, Columbia
Missouri, Kansas City
Nevada, Las Vegas
New Jersey, Hackensack
New Jersey, Somerset
New Jersey, Totowa
New Mexico, Albuquerque
New York, Albany*
New York, Bronx
North Carolina, Raleigh
North Carolina, Winston-Salem
Ohio, Cincinnati

Ohio, Cleveland
Ohio, Oakwood Village
Oklahoma, Tulsa
Oregon, Portland
Pennsylvania, Philadelphia
Puerto Rico, San Juan
South Carolina, Columbia
Tennessee, Gray
Tennessee, Knoxville
Tennessee, Nashville
Texas, Austin
Texas, Dallas *
Texas, Houston *
Utah, Salt Lake City
Virginia, Sterling
Washington, Seattle
Washington, Spokane
West Virginia, Morgantown
Wisconsin, Milwaukee

*2 manufacturing sites

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INDICATION

PYLARIFY (piflufolastat F 18) Injection is a radioactive diagnostic agent indicated for positron emission tomography (PET) of prostate-specific membrane antigen (PSMA) positive lesions in men with prostate cancer:

with suspected metastasis who are candidates for initial definitive therapy.
with suspected recurrence based on elevated serum prostate-specific antigen (PSA) level.

IMPORTANT SAFETY INFORMATION

Contraindications

None.

Warnings and Precautions

Risk of Image Misinterpretation

Imaging interpretation errors can occur with PYLARIFY imaging. A negative image does not rule out the presence of prostate cancer and a positive image does not confirm the presence of prostate cancer. The performance of PYLARIFY for imaging of patients with biochemical evidence of recurrence of prostate cancer seems to be affected by serum PSA levels. The performance of PYLARIFY for imaging of metastatic pelvic lymph nodes prior to initial definitive therapy seems to be affected by risk factors such as Gleason score and tumor stage. PYLARIFY uptake is not specific for prostate cancer and may occur with other types of cancer as well as non-malignant processes and in normal tissues. Clinical correlation, which may include histopathological evaluation of the suspected prostate cancer site, is recommended.

Hypersensitivity Reactions

Monitor patients for hypersensitivity reactions, particularly patients with a history of allergy to other drugs and foods. Reactions may be delayed. Always have trained staff and resuscitation equipment available.

Radiation Risks

Diagnostic radiopharmaceuticals, including PYLARIFY, expose patients to radiation. Radiation exposure is associated with a dose-dependent increased risk of cancer. Ensure safe handling and preparation procedures to protect patients and health care workers from unintentional radiation exposure. Advise patients to hydrate before and after administration and to void frequently after administration.

Adverse Reactions

The most frequently reported adverse reactions were headaches, dysgeusia and fatigue, occurring at rate of ≤2% during clinical studies with PYLARIFY. In addition, a delayed hypersensitivity reaction was reported in one patient (0.2%) with a history of allergic reactions.

Drug Interactions

Androgen deprivation therapy (ADT) and other therapies targeting the androgen pathway, such as androgen receptor antagonists, may result in changes in uptake of PYLARIFY in prostate cancer. The effect of these therapies on performance of PYLARIFY PET has not been established.

To report suspected adverse reactions for PYLARIFY, call 1-800-362-26681-80‌0-36‌2-2668 or contact FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

For important risk and use information about PYLARIFY Injection, please see Full Prescribing information.

REFERENCE

Data on file. Bedford, MA; Progenics Pharmaceuticals, Inc; 2024.

Availability and reliability assured with PYLARIFY

PYLARIFY imaging site locator

Closest Imaging Sites That Offer PYLARIFY® Near

INDICATION

Hypersensitivity Reactions

Radiation Risks

INDICATION

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Closest Imaging Sites That Offer
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